BRNO UNIVERSITY OF TECHNOLOGY, Faculty of Electrical Engineering and Communication Technologies (FEKT VUT)
Údolní 53, 602 00 Brno
MSM0021630503 “New trends in microelectronic systems and nanotechnologies (MICROSYN)”, (2005-2010), the research manager is Prof. Ing. Radimír Vrba, CSc.
Research intention puts stress on the issues of advanced microelectronic circuits, microsystems and structures on chips. All problem areas in the research task are focussed on new and perspective prepared micro, nanosystems, and technologies within the time horizon before the end of 2010. The task of the basic and applied research focuses on the five following research fields: 1. Theory, design and diagnostics of low voltage and a low intake integrated circuits in sub micron technologies, 2. Modelling and simulation of integrated circuits, 3. Microsystems and nanosystems, 4. Advanced technologies for microelectronics and nanoelectronics, 5. Modern diagnostics of materials and parts. Objectives of the research intention in its individual fields relate to the gaining of original results during the research of new microelectronic systems, progressive methods for their solution and optimising in the applied research of new micro and nanotechnologies for the preparation of new electronic structures and semiconductor parts of new generations.
The Institute of Physics develops, for a long time, activities within the Laboratory of the optical nanometrology under the leadership of Prof. RNDr. Pavel Tománek, CSc. The Laboratory organises non contact and non destructive research of material surfaces with the cause super differentiation and uses for it the optical lining tunnelling microscopy working within the reflection and permeable modes. The main objectives are the topography, local spectroscopy and the fluorescence of semiconductor surfaces, and the manufacture of probes for microscopes.
The Institute of Microelectronics, the Laboratory for the research and development of microsensors, is involved in the applications of nanomaterials in chemical sensors detecting heavy metals, measurable conductivity, and gases. In the field of thin layers, they focus on the research of techniques for the creation of MEMS and NEMS.
BRNO UNIVERSITY OF TECHNOLOGY, Faculty of Chemistry (FCH VUT)
Purkyňova 118, 612 00 Brno
MSM0021630501 “Multifunctional heterogeneous materials based on synthetic polymers and biopolymers”, (2005-2009), the research manager is Prof. RNDr. Josef Jančář, CSc.
The research intention is focussed on the research of advanced methods for the preparation and characterisation of heterogeneous materials, especially the polymer mixtures, nanostructures and composites, but also on the research of low dimension structures – the ultra-thin layers/multilayers.
In the Institute of Physical and Consumer Chemistry (the leading researcher is Doc. Ing. Miloslav Pekař, CSc.), the activities focus on the simulation of conformation relaxations of the chains of different sizes of the statistical segment and with different interaction potential between the nanoparticle surface and segments, including the effect of temperature and external force fields. The objective is the prediction of molecular structures of the chains either with the maximised or minimised nanoeffects. Activities of the institutes are also focussed on the study of transport phenomena in solid substances, the study of the molecular electronics, and the research of photochemical and photocatalytic processes at the molecular level.
The Institute of Material Chemistry (the leading researcher is Doc. RNDr. Vladimír Čech, PhD.) focuses its activities on the area of nanotechnologies related to the preparation, characterisation and application of thin and ultra-thin layers applied in the low temperature plasma (the plasma polymerisation) and with wet chemical processes (the sol-gel), or in their combination. Current works focus on the managed deposition of functionally nanostructured and gradient layers determined for the design of compatible interlayers usable for multicomponent materials (the composites and nanocomposites strengthened with fibres). The objective is the preparation of custom-made materials of beforehand defined physical-chemical properties.
The Institute of the Chemistry of Food and Biotechnologies (the leading researcher is Doc. Ing. Miroslav Fišera, CSc.) organises the research works belonging to the area of nanobiotechnologies. They are, for example, the isolation and characterisation of plant and bacterial enzymes usable in the industry (pectates, glucans, and the protease) and the possibility of their immobilisation and utilisation in the enzyme reactors. In the area of proteomics, this relates to the utilisation of microbial expressive systems for the manufacture of metabolites, food raw materials and components within the laboratory scale, with the possibility of a pilot plant adjustment.
INSTITUTE OF CHEMICAL TECHNOLOGY IN PRAHA, Faculty of Chemical Technology (FCHT VŠCHT)
Technická 5, 166 28 Praha 6
MSM6046137302 „Preparation and research of functional materials and material technologies with the use of micro and nanoscopic methods”, (2005-2009), the research manager is Doc. Ing. Aleš Helebrant, CSc.
The most important issue in the research intention is the study of relations between conditions of the material preparation and the material composition, structure and properties. This should allow for the targeted preparation and development of new kinds of materials with defined properties and for the improvement in properties and functions of their applications. From the application point of view, the research includes the three main following areas: 1) Materials for technological applications, 2) Materials for the human health, 3) Materials for the protection of the environment. The research shifts, in correspondence with the European and worldwide trends, to the area of nanomaterials and nano and microscopic layers. Objectives of the individual partial areas can be made more general and divide them into groups, which go across the individual areas:
· Finding and generalising the relations between the composition, structures and conditions of the preparation of special materials and substances with the beforehand selected chemical, pharmacological, physical and physical-chemical properties, and the development of chemical methodologies,
· Preparation of surface modifications and secondary surface layers on materials and their transfer into the technological practice,
· Optimising of technological processes, the application research in the area of new techniques and technologies with the utilisation of computer simulations,
· Clarification of physical-chemical processes taking place in material contacts with the surrounding environment and the design of ways utilised for the prevention of corrosion and material degradation,
· Modelling of material structures and processes during their preparation at the microscopic and nanoscopic levels, the development of analytical methods allowing for their verification.
There are two partial research projects solved within this research intention:
· “Preparation and properties of nanocrystalline metals”, the solvers - Ing. Jan Šerák, PhD. and Doc. Dr. Ing. Dalibor Vojtěch. The goal of this project is to prepare powders of nanocrystalline metals by different methods.
· “Nanocrystalline thermally stable aluminium alloys produced with the technology of powder metallurgy”, the solvers - Doc. Dr. Ing. Dalibor Vojtěch and Ing. Jan Verner. The project deals with the preparation and the study of properties of nanocrystalline aluminium alloys with transition metals (Cr, Ni, Fe, Zr, Ti, etc.). The alloys are manufactured with the technology of the powder metallurgy, which includes the ultra-fast cooling of melts and the compacting of the occurring powders.
The Institute of Inorganic Chemistry, in the team involved in superconductors and other materials based on transition metals, D. Sýkorová deals with the research that should improve the quality of high temperature superconductors by the use of nanotechnologies.
The Institute of Inorganic Technology, in the working group involved in catalytic processes, the issues of nanofiltration and projects focussed on nanotechnologies are solved by B. Bernauer, V. Fila, and J. Krýsa.
The Institute of Metallic Materials and the Corrosion Engineering solves the issues of nanocrystalline metals - D. Vojtěch and J. Šerák.
The Institute of Glass and Ceramics, the group dealing with the chemistry and technology of glass, is involved in the research of active surface nanolayers (J. Matoušek). Another involved worker is V. Hulínský.
The Institute of Solid Substance Chemistry, the group interested in the applied mineralogy - D. Koloušek, deals with the research of zeolite applications.
The Institute of Organic Chemistry, F. Hampl and R. Cibulka, they study the reactivity on the phase interface of nanoaggregates in micelles and microemulsions.
The Institute of Organic Technology deals with nanotechnologies in connection with the study of the material properties for catalysis, optoelectronics and the conversion of solar energy.
The Institute of Polymers organises the study of the synthesis of macromolecular substances, polymerisation mechanisms and the physical-chemical characteristics with the focus on the synthesis of polyamides, polyesters, polyesteramides, and their nanocomposites.
The Institute of the Solid Substance Engineering researches biomaterials for the tissue engineering (V. Švorčík), the materials for electronics and optoelectronics (I. Hüttel and J. Leitner), and the technologies for the preparation of thin layers by the pulse laser deposition (V. Myslík).
INSTITUTE OF CHEMICAL TECHNOLOGY IN PRAHA, Faculty of Chemical Engineering (FCHI VŠCHT)
Technická 5, 166 28 Praha 6
MSM6046137307 “Physical-chemical methods in the analysis and description of chemical systems and biosystems”, (2005 – 2009), the research manager is Prof. Ing. Karel Volka, CSc.
The subject of the research activities within the research intention is the gaining new or better quality physical-chemical data characterising the chemical and biochemical, or biological systems with the aim to describe or predict their thermodynamic properties and phase behaviour, to clarify their chemical composition and structures, to propose systems with defined analytical or other usable properties, or to suggest new analytical methods. The research focuses on several areas, including the following ones, which relate to nanotechnologies:
· Phase balances, fluid phase balances in systems with technological importance, the theoretical, pseudo-experimental and experimental studies of balanced and metastable phase transfers in macroscopic and nanostructured systems,
· Phenomena on phase interfaces and in membranes, in the inter-phase between the two fluid volume phases and between the solid and fluid phases, the sorption of long-term bio-toxic radionuclides on natural sorbents, the transport of gas and vapour mixtures through polymer membranes, the interaction on surfaces of nanoparticles and films.
The Institute of Analytical Chemistry, the Laboratory of the molecular recognition, Prof. RNDr. Vladimír Král, CSc. is leading the following works: The preparation and characterisation of nanoparticles, the modification of Au nanoparticles by selective receptors, the preparation of nanoparticles of metal-boron nanoclusters, the preparation of porphyrine nanoparticles for the utilisation in medicine, ceramic nanoparticles with photosensitisers for the PDT application, ceramic nanoparticles with immobilised metal-porphyrines for the catalysis (the oxygenation of olefines), the functionalisation of dendrimers.
The Institute of Chemical Engineering organises the studies of transport phenomena in the micro and nanostructured systems and executes theoretical and experimental analyses of possibly usable, especially chemical and biological, processes and their combinations, which might be done within the microscale more efficiently than within the macroscale, or which can be done only within the microscale (D. Šnita and J. Lindner).
UNIVERSITY OF WEST BOHEMIA IN PLZEŇ, Faculty of Applied Sciences (FAV ZČU)
Univerzitní 22, 306 14 Plzeň
MSM4977751302 “Processes in discharge plasma and new thin layer materials having unique properties”, (2005-2010), the research manager is Prof. RNDr. Jaroslav Vlček, CSc.
The subject of the research intention is the solution of fundamental problems in the area of the discharge plasma physics, plasma chemistry, the physics and engineering of surfaces, the physics of thin layers, the physics of solid substances, electrical engineering, and vacuum technologies in connection with the utilisation of thin layer materials of unique physical and functional properties. These materials are designed mainly in non conventional processes in the varied discharge plasma mostly by the magnetron and microwave discharges. The main attention is turned onto the modelling and diagnostics of not balanced discharge plasma, the study of layer growth processes and to the modification of surfaces, the design and research of new plasma sources for the deposition of thin layers and the surface modification, the characterising of created surfaces, and also to the study of thermomechanical processes taking place in materials. The research activities are focussed mainly on new nanostructured thin layer materials, the new thin layer materials based on ternary and four-ternary systems of carbon, silicon, boron, nitrogen, and other materials.
The issues related to nanostructured materials (layers) have made one part of the main directions for the Department of physics already for 10 years. There is the research of the technology for the preparation of layers (the magnetron sputtering, non conventional plasma processes), but also the research of these layers’ properties organised. The objective of these works is the practical application of the solution results.
VŠB – TECHNICAL UNIVERSITY IN OSTRAVA, Nanotechnology centre (CNT VŠB)
17.listopadu 15, 708 33 Ostrava-Poruba
MSM6198910016 “Synthesis, structure and properties of nanomaterials based on intercalated sheet silicates and ferromagnetics”, (2005-2011), the research manager is Prof. Ing. Jaromír Pištora, CSc.
The research intention focuses on the preparation and characterising of sheet silicate nanoparticles, which occur by the delaminating of precursors prepared in the intercalation way and which will be consequently used for the preparation of nanocomposite polymer-layered silicate. They test direct delaminating techniques (e.g. the mechanical micronisation, microwave procedures) and also in-mixing. Other nanomaterials of photofunctional, luminescent, sorption, catalytic properties (for the envisaged utilisation as the photofunctional units, sorbents for the immobilisation of gas and water pollutants), and catalytic effects (with the objective to utilise them for the selective reduction of nitrogen oxides). They will be prepared by the intercalation of organic molecules and polycations for the interlayers in sheet silicates. Special attention is paid to the analysis of their structural arrangement. A part of this objective is also the study of the role of sheet silicates in friction composites. They will also test the mechanical-physical and geometric properties of the studied nanoparticles of sheet silicates. The knowledge will be also utilised in the application of the model of an ideal loose material on plate structures.
PALACKY UNIVERSITY IN OLOMOUC, Faculty of Science (PřF UPOL)
tř. Svobody 26, 771 46 Olomouc
MSM6198959216 “Complex compounds and oxides of transition metals with the utilisation in bio-applications and nanotechnologies”, (2005-2011), the research manager is Prof. RNDr. Zdeněk Trávníček, PhD.
The intention envisages the synthesis of complex compounds of transition metals, oxides of transition metals, and elementary metals with properties suitable for their utilisation in bio-applications (cancerous statics) and in nanotechnologies (catalysis, biomagnetic separation, and nanopigments). The research activities consist of the three basic steps and includes progressively the synthesis of complex compounds and nanometarials, their complex physical-chemical characterisation, and the practical testing in selected areas of nanotechnologies and bio-applications. Among partial subjects of the research activities, we can mention the study of the mechanism of selected reactions in solutions, but also in the solid phase, or the study of the impact of surface adjustments and interparticle interaction on the magnetic properties of nanoparticles.
TOMÁŠ BAŤA UNIVERSITY IN ZLÍN, Faculty of Technology (FT UTB)
Náměstí T.G. Masaryka 275, 762 72 Zlín
MSM7088352101 „Multifunctional composite systems based on natural and synthetic polymers”, (2005-2011), the research manager is Prof. Ing. Petr Sáha, CSc.
The research intention focuses on the gaining new knowledge in the area of natural and synthetic macromolecular composite systems with the stress put on the dissemination of this knowledge in the sector of applied research. The selected multifunctional polymer composites with the inbuilt bio-part, optical, magnetic, or electric function, containing nanostructures, gel systems, or additive parts will be researched from the preparation, properties and processing points of view. The results should be new knowledge in the monitored areas, especially proposals of innovated products and manufacturing processes, including complex designs of management systems. It is envisaged that the achieved results will be used in the plastics, food, and automotive industries. Important benefits are expected also in the areas of healthcare materials and packaging.
Research in the area of nanotechnologies in the individual institutes:
Centre of polymer materials: The preparation and development of nanocomposites based on silver dendrimer-colloid for optical applications, modifications and studies of the nanostructured materials’ dimensionality, photovoltaic cells based on polymer volume heterotransitions (J. Šimoník, D. Měřínská, and A. Kalendová).
Institute of Polymer Engineering: The treatment of clay minerals by the intercalation and co-intercalation, the study of the product and intermediate product morphology, the technology for the preparation of polymer nanocomposites and the study of their properties (P. Sáha, F. Schauer).
UNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE, Institute of Physical Biology (ÚFB JČU)
Zámek 136, 373 33 Nové Hrady
MSM6007665808 “Physical biology – new approaches in the biological research”, (2005 – 2011), the research manager is Prof. RNDr. František Vácha, PhD.
The objective of the reserch intention is the utilisation of scientific physical, chemical and mathematical methods in the study of biology, from the level of an entire organism, the cell biology, and molecular biology to the biochemistry of proteins and individual biologically active molecules. The subjects of the study are the relations between the structure and the function of proteins, the molecular eco-physiology of the photosynthesis, photosynthetic biotechnologies, and the production of biologically active substances, the applied photobiology and imagining techniques, and the development of instruments. The objective is to contribute to the clarification of basic processes, molecular principles and regulations in the organism energy transformation, from individual proteins to the level of the entire organism.
Laboratory for nanobiology. The sector of the physical biology in the area of nanotechnologies deals with the development of approaches and methods for the high definition imagining of biological structures. The main researched topic is the imagining of the surface structure and the simultaneous monitoring of the function of protein complexes in the environment of the native membrane under physiological conditions, with the aid of the light microscopy and scanning probe microscopy.
Areál výzkumných ústavů, 19011 Praha 9
A part of the research intention MSM 2579700001 - the experimental stage “Research of the time and temperature dependency of the strength and fragility-fracture characteristics of engineering plastics and polymer nanocomposites”, (2005 – 2010), the solver is Ing. Jaroslav Hell, CSc.
The task objective in the area of construction polymers is the higher level of knowledge about the properties of thermoplastic nanocomposites during the creep straining in pulls and during the impact straining in multiple axis tension and in high speed deformation, including the problems of the mechanism of running disturbance processes.
COMTES FHT, s.r.o.
Lobezská E981, 326 00 Plzeň
MSM2631691901 “Metal materials with the structure in the sub micron and nanometric areas prepared by the method of intensive plastic deformation”, (2005 – 2009), the research manager is Prof. Ing. Jozef Zrník, CSc.
The research intention deals with the creation of ultra-fine – sub microscopic and nanostructural materials by the application of the intensive plastic deformation (by the ECAP, ARB, and HPT ways) at the same time, when the selected materials are exposed to the managed temperature. There were steels and aluminium alloys mostly selected for the experimental programme. Within the project, there are different kinds of deformation techniques applied and they are accompanied by different temperature modes. In addition to the existing techniques, which COMTES FHT, s.r.o. has got at its disposal, there are also other ones tested and developed. They are suggested and modified on the basis of the knowledge and experience obtained during the intention solution. The processed materials are analysed in detail from the microstructure point of view, but also from the properties point of view. The most important objectives of this task are as follows: The theoretical knowledge of mechanisms of making grains finer – down to the nanostructured form, the finding about the physical limits with regard to the grain sizes and the structure stability, and the achievement of required mechanical material properties.
Provider: Ministry of Health (MH)
INSTITUTE OF CLINICAL AND EXPERIMENTAL MEDICINE (IKEM)
Vídeňská 1958/9, 140 21 Praha 4, I.D. (IČO): 00023001
MZ0IKEM2005 “Research of cardiovascular diseases, diabetes, and transplants of vitally important organs”, (2005-2009), the research manager is Prof. R. Poledne, CSc.
The research intention in IKEM is focussed on the clinical and experimental research of cardiovascular diseases, diabetes and transplants, especially: The improvements in the surgery and catheterisation treatment of chamber tachycardia and the treatment of failures, the implementation of invasive detection vulnerable plates and the not invasive detection atherosclerosis for the improvement of the patient stratification, the optimising of the immunotherapy after transplants, the monitoring of the gene expression, and the immunodetection of the fraction complement and the tissue infections. It relates also to the gaining new knowledge about the key role played by the lipid mediators in the pathogenesis of the insulin resistance and the introduction of the transplanting method of the Langerhans islets into the clinical practice. The application of the MR imagining and the MR spectroscopy make parts of the most projects.
The intention includes partly the nanomedicine research. These applications focus on the molecular imagining – the area of the in vivo MR spectroscopy and applications of specific contrast substances based on nanoparticles.
INSTITUTE OF HAEMATOLOGY AND BLOOD TRANSFUSION (ÚHKT)
U nemocnice 1, 128 20 Praha 2, I.D. (IČO) 00023736
MZ0UHKT2005 “Importance of the molecular biological examination for the clarification of the pathogenesis, for the diagnostics of defects in blood creation, and for the utilisation of blood creating cells in the treatment of diseases related to the blood creation”, (2005-2011), the research manager is MUDr. Jaroslav Čermák, CSc.
The solution subject is the utilisation of molecular-biological examinations for the clarification of pathogenesis, for the diagnostics and treatment of defects in blood creation, the monitoring of the importance of changes in the structure and function of genome for the diagnostics, prognosis and treatment of inborn and gained diseases related to the blood creation. The monitoring of the importance of activation of individual parts of the coagulation system in tumour-related diseases of the blood creation, the clarification of the molecular fundamentals of the rare phenotypes of erythrocytes and some inborn defects of erythropoiesis, the utilisation of master blood creating cells in the treatment of diseases related to the blood creation and also in the treatment of other tissues, the handling of master blood creating cells for the cell therapy, the monitoring of the role played by blood creating cells in transplantations for the treatment of tumorous and other than tumorous diseases related to the blood creation, the monitoring of the safe mobilisation and separation of donors of blood creating cells obtained from the peripheral blood, and the monitoring of genetic factors influencing the success of transplants of blood creating cells.
The intention includes partly the nanomedicine research.
MASARYK ONCOLOGY INSTITUTE IN BRNO (MOÚ)
Žlutý kopec 7, 656053 Brno, I.D. (IČO) 00209805
MZ0MOU2005 “Functional diagnostics of malign tumours”, (2005 – 2011), the research manager is Doc. MUDr. Rostislav Vyzula, CSc.
The intention subject is the development and implementation of the new conception in the integrated functional diagnostics of solid malign tumours, which is based on a whole number of applied molecular-biological, cytodiagnostic, histocultivation, and imagining methods and which should efficiently supplement the existing purely morphologic diagnostics of tumours with new parameters representing individual properties of tumours at the beginning and during the antitumorous treatment. The objective is to improve the treatment results with better targeted and individual therapy.
The intention includes partly the nanomedicine research